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Primer on ADLM Respiratory Virus Testing Guidance
Cepheid

Cepheid

Editorial Team

4m Read

May 19, 2025

RESPIRATORY HEALTH

Article

A Quick Primer on the ADLM Guidance on Respiratory Virus Testing

Respiratory viral testing capabilities have advanced significantly in recent years and a variety of testing options exist, differing in the number of pathogens detected, viral markers, regulatory status, speed, and accuracy.

 

The Association for Diagnostics and Laboratory Medicine (ADLM) released expert recommendations and a decision-making algorithm to guide healthcare professionals on key aspects of testing for respiratory viral infections. We have reviewed this comprehensive resource and provide here a summary of the key recommendations as a quick primer.

Key Guidance Recommendations

Why, when, and who to test: there’s an algorithm for that!

 

The questions of whether, why, when, and who to test are critical for diagnostic stewardship. An algorithm was suggested to aid decision-making. Hospitalized patients with severe symptoms or underlying conditions and high-risk populations, such as older adults and immunocompromised individuals were prioritized for testing.

Suggested testing algorithm for respiratory viruses
Summary

Healthcare professionals must stay informed about evolving testing methodologies and guidelines to ensure accurate diagnosis, optimal patient management, and efficient resource utilization. This new guidance will assist healthcare practitioners in managing respiratory virus testing for improved clinical outcomes.

 

Click here to access the full ADLM guidance document.

Learn about Cepheid’s portfolio of targeted and multiplex respiratory virus NAAT tests here.

 

Abbreviations

EMR, electronic medical record; NPS, nasopharyngeal swab; IFU, instructions for use; NAAT, nucleic acid amplification test

Reference

Berry GJ, Jhaveri TA, Larkin PMK, Mostafa H, Babady NE. ADLM guidance document on laboratory diagnosis of respiratory viruses. [Epub] J Appl Lab Med May 2, 2024, as doi: 10.1093/jalm/jfae010.

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