Skin and soft tissue infections (SSTIs) are a major health concern:
The most common cause of skin and soft tissue infections is Staphylococcus; Methicillin-resistant Staphylococcus aureus (MRSA) ranges from 22.8% in Europe to 59% in the USA2
Current laboratory methods can take up to 72 hours to determine if a SSTI is Staphylococcus aureus (SA) or MRSA2
SSTIs require early recognition and prompt management as, depending on their severity, they can lead to considerable morbidity and mortality (3,4%) and represent a major economic burden to the healthcare system estimated to €7,778 per patient with 18,5 days of mean length of hospital stay2,3
The use of inappropriate initial antibiotic treatment can be associated with adverse clinical outcomes, increased morbidity and mortality, and increased hospital LOS or costs3
The initial empiric treatment has to be changed in around 40% of patients following the diagnostic results2
2. Garau J, et al. Current management of patients hospitalized with complicated skin and soft tissue infections across Europe (2010-2011): assessment of clinical practice patterns and real-life effectiveness of antibiotics from the REACH study. Clin Microbiol Infect. 2013 Sep;19(9):E377-85 3. Nathwani D, et al. Early clinical assessment of response to treatment of skin and soft-tissue infections: how can it help clinicians? Perspectives from Europe. Int J Antimicrob Agents. 2016 Aug;48(2):127-36 4. Package Insert Xpert® MRSA/SA SSTI 301-0190, Rev. E, January 2019
The Solution
A fast and comprehensive SSTI test:
Xpert MRSA/SA SSTI is a fast, on-demand test for detecting MRSA and SA from skin and soft tissue swabs in about one hour
Xpert MRSA/SA SSTI is a comprehensive SA test:
Includes targets for S. aureus, MRSA, and mecA
Identifies presumptive positive "empty cassette" strains for correct classification as SA sensitive
Unparalleled automation with the GeneXpert® System provides reduced hands-on time and improved laboratory efficiency
The Impact
Important healthcare benefits of rapid detection:1
Helps ensure the right therapy sooner for improved patient management
Enables a targeted antimicrobial therapy approach for better antimicrobial stewardship
Allows for immediate identification of patient infection for improved isolation and infection control measures
1. May LS, et al. A Randomized Clinical Trial Comparing Use of Rapid Molecular Testing for Staphylococcusaureus for Patients With Cutaneous Abscesses in the Emergency Department With Standard of Care. Infect Control Hosp Epidemiol. 2015 Dec;36(12):1423-30
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