CDI has become a substantive and growing burden in hospitalised patients prompting the need for earlier and accurate detection.
Xpert® C. difficile
- Fast identification of toxin-producing C. difficile in around 45 minutes
- Broad coverage with multiple targets, including: toxin B (tcdB), binary toxin (cdtA), and the tcdC deletion at base 117 associated with the ribotype 027 strain, a predictor of severe CDI and mortality8
- Optimised and prompt administering of therapy to support improved patient outcomes9
- Timely infection control initiatives to reduce the spread of infection10
- Laboratory efficiencies with on-demand workflows requiring minimal hands-on time and no repeat testing1,11
(1) Casari E, et al. Reducing rates of Clostridium difficile infection by switching to a stand-alone NAAT with clear sampling criteria. Antimicrob Resist Infect Control. 2018 Mar;7(40).(8) Rao K, et al. C. difficile ribotype 027: relationship to age, detectability of toxins A or B in stool with rapid testing, severe infection, and mortality. Clin Infect Dis. 2015 Jul 15;61(2):233-41.(9) Peppard W, et al. Implementation of polymerase chain reaction to rule out C. difficile infection is associated with reduced empiric antibiotic duration of therapy. Hosp Pharm. 2014 Jul;49(7):693-43.(10) Schroeder L, et al. Economic evaluation of laboratory testing strategies for hospital-associated Clostridium difficile infection. JCM. 2014 Feb;52(2):489.(11) Following C. difficile sampling guidance detailed in: McDonald L, et al. Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). Clin Infect Dis. 2018 Apr;66(7):e1–e48.CATALOG INFORMATION Xpert® C. difficile BT10 tests GXCDIFFBT-CE-10