Xpert® SA Nasal Complete
Pre-surgical S. aureus and MRSA in about 65 minutes
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10 Tests
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Collection Device (Pack of 50)
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The Need

S. aureus: An Ongoing Threat
  • Patients undergoing surgery are at increased risk of developing an infection1,2
  • S. aureus is the most common cause of SSIs1
  • Colonized patients are up to nine times more likely to develop an SSI1
  • SSIs are associated with increases in length of stay, cost, morbidity, and mortality1
  • Traditional direct culture testing takes 24+ hours to produce a result, and may risk under-detecting positive cases2
(1) Kluytmans J, et al. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks. Clin Microbiol Rev. 1997 Jul;10(3):505-20.
(2) Piraino B. Staphylococcus aureus infections in dialysis patients: focus on prevention. ASAIO J. 2000 Nov-Dec;46(6):S13-7.

The Solution

SSIs caused by S. aureus continue to present a substantive burden in healthcare settings, prompting the need for earlier and more accurate pre-admission identification.
Xpert® SA Nasal Complete enables:
  • Fast identification and differentiation of S. aureus and MRSA in around 60 minutes
  • Broad coverage with multiple targets, including: the orfXSCCmec junction, mecA gene and spa gene for more accurate S. aureus and MRSA detection
  • Optimised pre-admissions pathway for improved patient outcomes
  • Appropriate decolonization measures to reduce SSIs and the development of new resistances
  • Laboratory efficiencies with on-demand workflows requiring minimal hands-on time

The Impact

Fast and accurate PCR testing with Xpert® SA Nasal Complete greatly improves time to result, allowing healthcare professionals to quickly and appropriately manage pre-surgical admissions, reducing infection risk, transmission, and patient length of stay.
Optimize Workflow and Patient Management
  • Deliver fast and actionable results to surgical and infection control teams in around 60 minutes
  • On-demand STAT testing provides results 24/7
  • Ease of use and minimal hands-on-time enables more efficient use of staff time
(3) Critchley IA. Eradication of MRSA nasal colonization as a strategy for infection prevention. Drug Discov. Today. 2006;3(2):189-95.
(4) Yu VL, et al. Staphylococcus aureus nasal carriage and infection in patients on hemodialysis. Efficacy of antibiotic prophylaxis. N Engl J Med. 1986 Jul 10;315(2):91-6.
(5) Murphy D, et al. Dispelling the Myths: The True Cost of Healthcare-Associated Infections. An APIC Briefing. 2007 Feb. Accessed May 2020. http://www.thainapci.org/download-guideline-6.pdf/
(6) Engemann JJ, et al. Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus aureus surgical site infection. Clin Infect Dis. 2003 Mar 1;36(5):592-8. Epub 2003 Feb 7.
(7) Anderson, DJ. Clinical and Financial Outcomes Due to Methicillin Resistant Staphylococcus aureus Surgical Site Infection: A Multi-Center Matched Outcomes Study. PLOS One. 2009 Dec 15. Accessed May 2020. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008305
(8) Bode LG, et al. Preventing Surgical-Site Infections in Nasal Carriers of Staphylococcus aureus. N Engl J Med. 2010 Jan 7;362:9-17.
(9) Mackie DP, et al. Reduction in Staphylococcus aureus wound colonization using nasal mupirocin and selective decontamination of the digestive tract in extensive burns. Burns. 1994;20 Suppl 1:S14-7; discussion S17-8.
(10) Kooistra-Smid M, et al. Molecular epidemiology of Staphylococcus aureus colonization in a burn center. Burns. 2004 Feb;30(1):27-33.
(11) Noskin GA, et al. The Burden of Staphylococcus aureus Infections on Hospitals in the United States. Arch Intern Med.2005;165(15):1756–1761.

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