Xpert® SA Nasal Complete

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Pre-surgical S. aureus and MRSA in about 65 minutes

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10 Tests

GXSACOMP-CE-10

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The Need

S. aureus: An Ongoing Threat

Patients undergoing surgery are at increased risk of developing an infection^1,2
S. aureus is the most common cause of SSIs¹
Colonized patients are up to nine times more likely to develop an SSI¹
SSIs are associated with increases in length of stay, cost, morbidity, and mortality¹
Traditional direct culture testing takes 24+ hours to produce a result, and may risk under-detecting positive cases²

(1) Kluytmans J, et al. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks. Clin Microbiol Rev. 1997 Jul;10(3):505-20.
(2) Piraino B. Staphylococcus aureus infections in dialysis patients: focus on prevention. ASAIO J. 2000 Nov-Dec;46(6):S13-7.

The Solution

SSIs caused by S. aureus continue to present a substantive burden in healthcare settings, prompting the need for earlier and more accurate pre-admission identification.
Xpert^® SA Nasal Complete enables:

Fast identification and differentiation of S. aureus and MRSA in around 60 minutes
Broad coverage with multiple targets, including: the orfXSCCmec junction, mecA gene and spa gene for more accurate S. aureus and MRSA detection
Optimised pre-admissions pathway for improved patient outcomes
Appropriate decolonization measures to reduce SSIs and the development of new resistances
Laboratory efficiencies with on-demand workflows requiring minimal hands-on time

The Impact

Fast and accurate PCR testing with Xpert^® SA Nasal Complete greatly improves time to result, allowing healthcare professionals to quickly and appropriately manage pre-surgical admissions, reducing infection risk, transmission, and patient length of stay.
Optimize Workflow and Patient Management

Deliver fast and actionable results to surgical and infection control teams in around 60 minutes
On-demand STAT testing provides results 24/7
Ease of use and minimal hands-on-time enables more efficient use of staff time

(3) Critchley IA. Eradication of MRSA nasal colonization as a strategy for infection prevention. Drug Discov. Today. 2006;3(2):189-95.
(4) Yu VL, et al. Staphylococcus aureus nasal carriage and infection in patients on hemodialysis. Efficacy of antibiotic prophylaxis. N Engl J Med. 1986 Jul 10;315(2):91-6.
(5) Murphy D, et al. Dispelling the Myths: The True Cost of Healthcare-Associated Infections. An APIC Briefing. 2007 Feb. Accessed May 2020. http://www.thainapci.org/download-guideline-6.pdf/
(6) Engemann JJ, et al. Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus aureus surgical site infection. Clin Infect Dis. 2003 Mar 1;36(5):592-8. Epub 2003 Feb 7.
(7) Anderson, DJ. Clinical and Financial Outcomes Due to Methicillin Resistant Staphylococcus aureus Surgical Site Infection: A Multi-Center Matched Outcomes Study. PLOS One. 2009 Dec 15. Accessed May 2020. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008305
(8) Bode LG, et al. Preventing Surgical-Site Infections in Nasal Carriers of Staphylococcus aureus. N Engl J Med. 2010 Jan 7;362:9-17.
(9) Mackie DP, et al. Reduction in Staphylococcus aureus wound colonization using nasal mupirocin and selective decontamination of the digestive tract in extensive burns. Burns. 1994;20 Suppl 1:S14-7; discussion S17-8.
(10) Kooistra-Smid M, et al. Molecular epidemiology of Staphylococcus aureus colonization in a burn center. Burns. 2004 Feb;30(1):27-33.
(11) Noskin GA, et al. The Burden of Staphylococcus aureus Infections on Hospitals in the United States. Arch Intern Med.2005;165(15):1756–1761.